Saturday, 29 June 2024

Glue berry..../लसोड़ा

 अध्ययन बताते हैं कि लसोड़ा की छाल और फल में बहुत से औषधीय गुण होते हैं। शारीरिक ताकत में सुधार के अलावा छाल के काढ़ा का इस्तेमाल घाव व डायरिया को ठीक करने और आंतों के कीड़ों को मारने में किया जाता है लसोड़ा के हर हिस्से का प्रयोग स्थानीय समुदाय द्वारा परंपरागत रूप से किया जाता है।







For knowledga of common people about uses of indian herbs..


Thanks friends for your visit.

If any query please wrire at

email; bioworld@hotmail.com

Bioworldhc@gmail.com.

https://bioworldhealthcare.blogspot.com/





Friday, 15 March 2024

Treatment of liver. NASH new information.

                                     FDA approved .... 

                                A new development for 

                              Treatment of liver.

Wednesday, 13 March 2024

अश्वगंधा / Withania somnifera


अश्वगंधा / Withania somnifera  


अश्वगंधा / Withania somnifera    An anti inflammatory and immune booster Due to its properties, Withania somnifera is being studied for the treatment of many diseases associated with inflammation in the body, such as cardiovascular, pulmonary, and autoimmune diseases and diabetes, cancers, and neurodegenerative diseases.

Turmeric, ashwagandha and more than 500 other medicinal plants are potential recruits for the war on cancer at Mumbai-based Tata Memorial Centre (TMC). While many scientists will arch their eyebrows at this news, TMC is setting up a farm and a 100-bed hospital-cum-research facility in Khopoli near Mumbai to grow plants and test their efficacy in cancer treatment.

 Fruits of Withania somnifera .


Highlights

  • Clinical safety and tolerability of standardized Withania somnifera (L.), Dunal root extract at 1000 mg daily in healthy male volunteers were evaluated.

  • Throughout the trial, a comprehensive range of assessments was conducted, including monitoring vital signs, CBC, lipid profile, TFT, LFT, KFT, urine analysis, serum B12, and C-reactive protein levels.

  • The study commenced and concluded with evaluating X-rays, electrocardiograms, and cardiorespiratory endurance as determined by VO2 max and anthropometric parameters.

  • The clinical examination and laboratory analysis indicates that W. somnifera root extract . was effectively tolerated by healthy participants, and no adverse effects were observed.

Objective

This research evaluated the tolerability and safety of standardized Withania somnifera root extract (WSE) capsules . at 1000 mg/day dose upon oral administration in healthy male participants.

Method

A non-randomized, open-label, single-treatment clinical study included eighteen healthy male participants aged 18 to 60. The participants were administered a dose of 500 mg of the WSE capsules twice daily for four weeks. Each capsule contained not less than 7.50 mg of total withanolides. The study evaluated various indicators in a cohort of healthy participants throughout the trial, including vital signs, organ function tests, urine analysis, X-ray and ECG, cardiorespiratory endurance, body fat percentagelean body weight, adverse events profile, and tolerability of the WSE capsules.

Results

The participant's physical, hematological, and biochemical characteristics were normal, and no significant alterations or irregularities were observed in safety metrics like liver, kidney, and thyroid functions after administering.

Conclusion

This study found that healthy male participants could consume a standardized WSE at a daily dosage of 1000 mg for four weeks without any adverse effects. Future research should focus on long-term safety assessments in male and female participants.

According to AyurvedaW. somnifera leaves can be applied externally. Further, as per ethnopharmacological evidence, the paste of leaves is applied to painful areas, and boiling leaves are applied topically to treat boils and reduce pain .. Ayurveda advises the use of only roots for ingestible administration and therapeutic purposes. The Indian Ministry of ‘AYUSH', Government of India, recently released an advisory urging people to “refrain from the use of W. somnifera leaves" due to the lack of “substantial evidence and literature" in favor of the use of Ashwagandha leaves as medicine.The use of additional plant parts, particularly the leaves and stem, of the W. somnifera, could have blended with root material and/or its extract for commercial purposes, which, beyond adulteration concern, may lead to adverse effects. Commercial extracts with inadequate quality control pose a risk to consumers, researchers, and regulatory organizations who expect material consistency and quality parameters. In 2023, the Indian Ministry of AYUSH also published a safety dossier on W. somnifera, analyzing 27 toxicity studies. They concluded that using W. somnifera root extract at a concentration dose of at least 2,000 mg/kg body weight is safe for human consumption without any negative impact .

Numerous clinical trials on Ashwagandha for treating schizophrenia, neuropathic pain, anxiety, stress, ADHD, memory and cognitive enhancement, sexual health in men and women, cardio-respiratory endurance, hyperlipidemia, and COVID-19 have been reported  However, a significant problem for the worldwide nutraceuticals and dietary supplement industry and various countries' regulatory bodies could be Ashwagandha's safety. Relatively few adequate investigations on the safety of Ashwagandha have been published. According to Raut et al.'s (2012) study, W. Somnifera roots were well tolerated when administered as an aqueous extract in capsules with gradually increasing doses of 750–1250 mg/day [32]. Recent research by Verma et al. (2021) on the safety of ashwagandha root extract in healthy volunteers at a dose of 600 mg/day shows that both male and female participants could take the supplement for eight weeks without experiencing any side effects  Chandrasekhar et al. (2012) reported the ashwagandha root extract for lowering adult stress and anxiety, in which six mild side effects were reported, including drowsiness and a decreased appetite [34]. In a study by Choudhary et al. (2017), two individuals using Ashwagandha root extract for memory and cognitive enhancement reported experiencing minor giddiness, a heavy head, blurred vision, and/or hyperacidity . The effectiveness and safety of ashwagandha root extract were later reported by Sharma et al. (2018) in subclinical hypothyroid patients, where one participant reported an adverse event with symptoms of mild, transient fever, asthenia, and cough [23].

Variations of commercially available WSE (including roots, leaf, or combining root and leaf extracts) are marketed globally as foods, beverages, and dietary supplements. These extracts are standardized with various analytical techniques and contain varying concentrations of withanolides (1%–5% to 35% total withanolides). More in-depth data is needed to grasp the clinical safety of the standardized WSE in the healthy population. The current study intends to investigate the safety and tolerability of WSE standardized to not less than 7.50 mg of total withanolides per capsule at a dose of 500 mg twice daily in 18 healthy male participants following repeated intake for four weeks to close this knowledge gap. Based on this study's clinical findings, standardized WSE can be successfully introduced into the global nutraceutical market while ensuring adequate safety and biological activity as a highly potent botanical ingredient.

. Study design

A four-week, open-label, non-randomized clinical trial was conducted to assess the safety of WSE on healthy human volunteers. The study's primary goal was to determine the safety of WSE (AgeVel®/Witholytin®) capsules when administered to healthy human male volunteers. The study's secondary goal was to establish the product's safety and tolerability by keeping track of adverse events.

Informational in this article is collected from different  sources  and internet. This is for public awareness  and information  only.



email us at : bioworldhc@gmail.com
  • https://bioworldhealthcare.blogspot.com/



Thanks for your visit.


Sunday, 3 March 2024

Porce : Gift of Nature to Humanity..

                                   Gifts of nature to humanity







Write your reviews..

  • https://bioworldhealthcare.blogspot.com/
  • email : bioworldhc@gmail.com


Thursday, 29 February 2024

Coriender benifits as spices

Coriender benifits as spices





  • https://bioworldhealthcare.blogspot.com/
  • email : bioworldhc@gmail.com


Monday, 7 August 2023

Lemon nutritional information

Lemon Nutrients,






Nutritional facts about juice of Lemon..
mail us at :
bioworldhc@gmail.com.

 

Tuesday, 1 August 2023

Rock salt best for health

 

                                                           Sendha Namak (Rock Salt)




Sendha namak is the Indian name for Himalayan rock salt. It is a large-grained, coarse salt, also called halite or land salt, that's available in many grocery and health food stores. It dissolves readily in water. Here are some more key things to know about this delicious salt:

Sendha namak is mined from underground deposits of dried lakes in the Punjab region of Pakistan. It is unrefined, non-iodized and contains no additional anti-caking agents. It can be white, pink, red, or even blue in color.

It is lower in sodium than regular table salt and contains 94 trace minerals, as opposed to the three that are in common table salt. Since this salt is pure, it is used during religious fasts in India.

It is used in Ayurvedic medicine. It is said to be good for the heart, beneficial for people with diabetes and to prevent osteoporosis. According to Ayurveda, this salt reduces depression and stress, prevents and treats muscle cramps, regulates blood pressure, aids digestion, and relieves skin problems and arthritis.

In India, it is used in making chutneys, raita (yogurt sauces), chaats, snacks, and other dishes.

This salt lowers the freezing point of water and can be used in ice cream machines.

Research has shown that Sendha salt is more beneficial than other edible salts for patients suffering from chronic kidney disease.

Kala Namak (Black Salt)

Black salt, or Kala namak, is dark brown (almost black) but changes to a pinkish-grey powder when it's ground. It is also referred to as sanchal.

It has a sulfurous smell—much like boiled eggs—from its natural sulphur content.

Kala namak is rich in iron, which is why it is so dark in color.

This salt is harvested from the natural salt mines in Northern India and Pakistan.

Black salt is used extensively in Ayurvedic medicine, and as a condiment in Indian cooking. It's added to chaat, chutneys, and even sprinkled on fruits and other Indian snacks before eating. It tastes great on cut vegetables, too.

Black salt is low in sodium. It is used in Ayurvedic medicine to treat indigestion, constipation, gas, and heartburn. It is also used to treat high blood pressure and anemia


  • https://bioworldhealthcare.blogspot.com/
  • email : bioworldhc@gmail.com

Nutmeg...Jayfal Ayurvedic Medicine.

  Nutmeg...Jayfal Ayurvedic Medicine. Jaifal- Health Benefits The Ayurvedic spice jaiphal or jaifal is used in dishes all around the world...